Development of LC-MS/MS method for determination of mesalazine and vV-Ac-5-ASA in rat plasma, U-rine and colon
- Author:
Zhi RAO
1
Author Information
- Publication Type:Journal Article
- Keywords: LC-MS/MS; Mesalazine; N-Ac-5-ASA
- From: Chinese Pharmaceutical Journal 2014;49(14):1252-1257
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To develop an LC-MS/MS method for determination of mesalazine and its metabolite, N-Ac-5-ASA, in rat plasma, urine and colon for the pharmacokinetic study of mesalazine and N-Ac-5-ASA in rats.