Antioxidative effect of rhodiola granules in vitro and in vivo
- Author:
Jun-Ling CAO
1
Author Information
- Publication Type:Journal Article
- Keywords: Antioxidation; In vitro and in vivo; Rhodiola granule
- From: Chinese Pharmaceutical Journal 2014;49(14):1222-1225
- CountryChina
- Language:Chinese
- Abstract: METHODS: Female Kunming mice were randomly divided into five groups, ie, blank control group, low-dose group, middle-dose group, high-dose group, and the positive control group. The three treatment groups were given various doses of Rhodiola granules, ie, 0. 1, 1, 3 g��kg-1 respectively, the positive control group were given Nuodikang capsules at 280 mg��kg-1, and the blank control group was given deionized water for 35 d. The levels of SOD, MDA, GSH-PX in serum, liver, and brain were determined. For the experiment in vitro, with vitamin C as the control drug, the absorbance of Rhodiola granule solution at concentrations of 0.01, 0.1, 1, 10 mg��mL-1 was measured, and the activity of scavenging superoxide anion free radicals and hydroxyl free radicals was calculated.
