Research progress in role and mechanism of endogenous cannabinoid system in hepatic disease
10.11669/cpj.2014.02.001
- Author:
Chun-Feng LU
1
Author Information
1. College of Pharmacy
- Publication Type:Journal Article
- Keywords:
Alcoholic fatty liver;
Cholestatic liver disease;
Endogenous cannabinoid system;
Hepatic encephalopathy;
Hepatic fibrosis;
Hepatic ischemia/reperfusion injury;
Non-alcoholic fatty liver disease
- From:
Chinese Pharmaceutical Journal
2014;49(2):89-93
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To analyze recent studies on the role of the endocannabinoid system in liver disease and related mechanism. METHODS: Reading domestic and international documents in recent years, we concluded a comprehensive integrated about them. RESULTS: This paper reviews the important role of the endocannabinoid in the development of liver disease, which focuses on the prevention and protection of the endocannabinoid on viral hepatitis, alcoholic fatty liver disease, non-alcoholic fatty liver disease, cholestatic liver disease and liver ischemia-reperfusion injury and the development of hepatic fibrosis and hepatic encephalopathy. CONCLUSION: Endocannabinoid system plays an important role in the treatment of liver disease. But for its complex mechanism of action, we need further research.
