Proliferative Glomerulopathy with Unusual Subendothelial Deposits of Striated Structure in Multiple Myeloma.
- Author:
Yun Gyoo LEE
1
;
Dong Yeop SHIN
;
Hyun Jung LEE
;
Se Youn CHOI
;
Jae yoon PARK
;
Shin young AHN
;
Hajung LEE
;
Yunjung OH
;
Kyung Chul MOON
;
Kook Hwan OH
;
Inho KIM
Author Information
1. Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. kim_dajung@hanmail.net
- Publication Type:Case Report
- Keywords:
Membranoproliferative glomerulonephritis;
Deposit;
Striated;
Monoclonal gammopathy
- MeSH:
Biopsy;
Bone Marrow;
Female;
Glomerulonephritis, Membranoproliferative;
Humans;
Middle Aged;
Multiple Myeloma;
Paraproteinemias;
Proteinuria
- From:Korean Journal of Nephrology
2010;29(6):772-775
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 50-year-old woman was admitted for the evaluation of proteinuria and renal biopsy. On the basis of the serum monoclonal protein, marrow plasma cell dyscrasia and end organ damage (nephrotic range proteinuria), multiple myeloma was diagnosed. A renal biopsy showed a membranoproliferative glomerulonephritis pattern of injury and unusual organized deposits of striated structure in the subendothelial space, which were identified as non-amyloid non-immunoglobulin-derived deposits. These deposits contained regularly stacked straight electron-dense bands, which have not been described in the setting of paraproteinemia and/or plasma cell dyscrasia.
