Chemical constitutents in the fruits of Gardenia jasminoides var. radicans Makino
- Author:
Fang-Min QIN
1
Author Information
- Publication Type:Journal Article
- Keywords: Gardenia; Gardenia jasminoides var. radicans Makino; Iridoid glycoside; Quercetin; Quinic acid
- From: Chinese Pharmaceutical Journal 2014;49(4):275-278
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To study the chemical constituents in the fruits of Gardenia jasminoides var. radicans Makino. METHODS: Percolation with alcohol and liquid-liquid extraction methods were used to extract the constituents. And silica gel, reverse-phase octadecylsilyl(ODS), and sephadex LH-20 chromatographic methods were applied to isolate and purify compounds. MS, NMR spectroscopic methods were used to elucidate their structures. RESULTS: Ten compounds were isolated from the ethyl acetate fraction of the ethanolic extract of fruits from Gardenia jasminoides var. radicans Makino, and their structures were identified as seven iridoids: geniposide (1), 6α-hydrogeniposide (2), 6β-hydrogeniposide (3), 6α-methoxygeniposide (4), 6β-methoxygeniposide (5), 2'-O-(4″-Hydrooxycinnamoyl) mussaenosidic acid(6), 6″-O-trans-p-coumaroylgenipin genitiobioside(7); two quinic acid derivatives: 3, 5-di-O-caffeoyl-4-O-(3-hydroxyl-3-methyl) glutaroylquinic acid(8), methyl 3, 5-di-caffeoyl-4-O-(3-hydroxy-3-methyl)-glutaroylquinate(9); and one flavonoid: quercetin-3-O-β-D-glucopyranoside(10). CONCLUSION: Compounds 3-10 are isolated from Gardenia jasminoides var. radicans Makino for the first time.
