A Case of Pulmonary Adenocarcinoma Developed on a Previous Lesion from Microscopic Polyangiitis.
- Author:
Jae yoon PARK
1
;
Seong woo LEE
;
Shin Young AHN
;
Jong Cheol JEONG
;
Sunghae CHANG
;
Tae Woo LEE
;
Kook Hwan OH
;
Hojun CHIN
;
Kwon Wook JOO
;
Yon Su KIM
;
Curie AHN
;
Jin Suk HAN
;
Jeong wook SEO
;
Suhnggwon KIM
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. skimim@plaza.snu.ac.kr
- Publication Type:Case Report
- Keywords:
Microscopic polyangiitis;
Adenocarcinoma;
Anti-neutrophil cytoplasmic antibodies
- MeSH:
Adenocarcinoma;
Antibodies, Antineutrophil Cytoplasmic;
Dyspnea;
Female;
Follow-Up Studies;
Glomerulonephritis;
Humans;
Lung;
Microscopic Polyangiitis;
Middle Aged;
Physical Examination;
Positron-Emission Tomography;
Prednisolone;
Serologic Tests;
Thoracic Surgery, Video-Assisted;
Thorax
- From:Korean Journal of Nephrology
2010;29(6):787-791
- CountryRepublic of Korea
- Language:English
-
Abstract:
This report examines a patient with pulmonary adenocarcinoma that developed on a previous lesion from microscopic polyangiitis. A 59-year-old woman had been diagnosed with microscopic polyangiitis in October of 1988 based on her clinical symptoms and serological tests, which were positive for anti-neutrophil cytoplasmic antibodies. Her glomerulonephritis had been well controlled with low-dose prednisolone. She presented in October of 2005 with vague chest discomfort and dyspnea on exertion. Physical examination was unremarkable. A non-contrast computed tomography (CT) scan of the chest showed patch ground-glass opacity at the right lower lobe of the lung. Because we did not believe the lesion to be a definite malignancy, we decided to follow up with chest images over a short interval. During the 18 months following the images, the lesion did not change. However, the opacity of the lesion increased slightly over the last two months, and a non-contrast CT scan of the chest was therefore performed. A CT scan showed persistent ground-glass opacity with a slightly solid portion. To diagnose the previous finding and possibly to provide treatment, a right lower lobectomy of the lung via video-assisted thoracoscopic surgery was performed. The pathologic review of the resected lung revealed an adenocarcinoma, stage pT1N0. After one year, fluorodeoxyglucose positron emission tomography was performed, and no evidence of a recurrent malignancy was found.
