A Case of Plasmodium vivax Malaria Complicated with Acute Renal Failure, Jaundice and Thrombocytopenia.
- Author:
Hyun Jung KIM
1
;
Seo Hyun LEE
;
Tai Yeon KOO
;
Kyung Min KIM
;
Sung Soo JANG
;
Sang Koo LEE
Author Information
1. Division of Nephrology, Asan Medical Center, University of Ulsan, Seoul, Korea. sklee2@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Plasmodium vivax;
Jaundice;
Thrombocytopenia;
Acute renal failure
- MeSH:
Acute Kidney Injury;
Anemia;
Bilirubin;
Blood Platelets;
Blood Urea Nitrogen;
Creatinine;
Diagnosis, Differential;
Erythrocytes;
Fever;
Hemoglobins;
Humans;
Jaundice;
Korea;
Leptospirosis;
Malaria;
Malaria, Vivax;
Male;
Middle Aged;
Plasmodium;
Plasmodium vivax;
Pulmonary Edema;
Rickettsia;
Serologic Tests;
Thrombocytopenia;
Trophozoites;
Viruses
- From:Korean Journal of Nephrology
2010;29(6):792-795
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malaria is caused by four species of the genus Plasmodium. Plasmodium vivax malaria is the most common malarial infection in Korea and usually has benign clinical course. However, serious complications such as severe anemia, pulmonary edema, acute renal failure are reported in Plasmodium vivax malaria. We report a case of Plasmodium vivax malaria complicated with acute renal failure, jaundice and thrombocytopenia. A 56-year-old male was transferred to our hospital with acute renal failure, jaundice and thrombocytopenia. 10 days before admission, he had intermittent fever, chill, myalgia, and was treated with some medications under the impression of URI. Laboratory findings showed that hemoglobin was 11.5 g/dL, platelet 44,000/mm3, blood urea nitrogen 73 mg/dL, creatinine 4.0 mg/dL, total bilirubin 5.2 mg/dL, direct bilirubin 4.0 mg/dL. Serologic tests for leptospirosis, rickettsia, EB virus and CMV were negative. Ring form trophozoites were found in red blood cells, suggesting Plasmodium vivax malaria. Following anti-malarial therapy, acute renal failure, jaundice and thrombocytopenia were recovered to normal. From this case, malarial infection should be included as a differential diagnosis in a febrile patient with acute renal failure, jaundice and thrombocytopenia.
