Application of FTIR in specified microorganisms source tracking for pharmaceutical products
- Author:
Wei-Sheng CHEN
1
Author Information
- Publication Type:Journal Article
- Keywords: FTIR; Microbial source tracking; Ribotyping; Specified microorganism
- From: Chinese Pharmaceutical Journal 2015;50(19):1715-1720
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To preliminarily explore the application of FTIR in microbial source tracking for specified microorganisms in pharmaceutical products. METHODS: The repeatability, intermediate precision, and accuracy of FTIR were investigate in selected conditions. RESULTS: Under standard operation and culture conditions, the repeatability, intermediate precision, and accuracy of FTIR met the basic requirements for microbial source tracking as judged by a threshold value of similarity index of greater than 0.95. The tracking results of 12 bacterial strains were almost the same as RiboPrinter analysis. CONCLUSION: FTIR is economic and fast. It is advantageous for promotion of specified microorganisms source tracking in enterprises.
