Research progress of synthesis and pharmacological activity of pyrazolo3, 4-d pyrimidine derivatives
- Author:
Mei-Rong ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Pharmacological activity; Pyrazolo[3, 4-d] pyrimidine derivative; Synthesis
- From: Chinese Pharmaceutical Journal 2015;50(3):194-200
- CountryChina
- Language:Chinese
- Abstract: Due to the extensive pharmacological effects, pyrazolo[3, 4-d] pyrimidine derivatives have aroused great attention. There are a variety of ways in their synthesis, including using pyrazole ring, pyrimidine ring and other materials as parent ring. The compounds have strong bactericidal, anti-inflammatory, anti-cancer and anti-virus activities, etc. In this paper, the synthesis and pharmacological activities of pyrazolo[3, 4-d] pyrimidine derivatives taking the synthesis as the main line are summarized.