Identification study of glue medicines
- Author:
Xian-Long CHENG
1
Author Information
- Publication Type:Journal Article
- Keywords: Glue medicine; LC-MS; Marker peptide; PCA; Quality control; Quality standard
- From: Chinese Pharmaceutical Journal 2015;50(2):104-108
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To find the marker peptides of five kinds of glue medicines including deerhorn glue, tortoise shell glue, donkey-hide gelatin, bovine-hide gelatin, and pig-hide gelatin. METHODS: The characteristic peptides of different gelatins were identified by tripsin digestion and HPLC-MS/MS. RESULTS: The marker peptides of five glue medicines were found, ie, donkey-hide gelatin m/z 539.8, deerhorn glue m/z 765.4, tortoise shell glue m/z 631.3, bovinehide gelatin m/z 641.3, pig-hide gelatin m/z 774.5, and the methods which can be used to identify the glue medicines were established according to the marker peptides. CONCLUSION: The marker peptides that we found can be used for the identification of glue medicines.
