Establishment of national reference panel for methamphetamine Kits

Author: Ning ZUO ¹
Author Information

1. National Institutes for Food and Drug Control
Publication Type:Journal Article
Keywords: LC-MS; Methamphetamine kits; National reference panel
From: Chinese Pharmaceutical Journal 2016;51(15):1330-1335
CountryChina
Language:Chinese
Abstract: OBJECTIVE: To establish the reference panel of methamphetamine (MET) Kits. METHODS: After determining the cut-off value of MET kits, selecting the raw material, and determining the component of reference material, MET kits reference material was prepared. The reference material was characterized by verified LC-MS method, and also tested for the stability. RESULTS: The national reference material of MET kits consists of one positive sample, 12 negative samples, three LOD samples, and one repeatability sample. This reference material passed the co-characterization of five companies. CONCLUSION: The developed national reference material of MET kits meets the corresponding requirement. The establishment of the national reference material of MET kits may help regulate the development and production process of the drug kits.