Effect of rice wine on degradation of 3,29-dibenzoyl karounitriol in Gualou-Xiebai in human intestinal flora
- Author:
Chun-Cai ZOU
1
Author Information
- Publication Type:Journal Article
- Keywords: Cites drug; Intestinal flora; Rice wine
- From: Chinese Pharmaceutical Journal 2017;52(1):53-56
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To study the effects of rice wine on the metabolism of 3, 29-dibenzoyl karounitriol as the main active component in Gualou-Xiebai in human intestinal flora, exploring the scientific connotation of Gualou-XiebaiBaijiu Decoction from the angle of metabolism. METHODS: The metabolic rate of 3, 29-dibenzoyl karounitriol in Gualou-Xiebai rice wine solution and aqueous solution at different time points were compared,respectively,by intestinal flora experiments. RESULTS: Compared to Gualou-Xiebaiaqueous solution group, the metabolic rate of 3, 29-dibenzoyl karounitriol in Gualou-Xiebai rice wine solution group decreased significantly (P<0.05). CONCLUSION: Rice wine as cites drug can inhibit the metabolism of 3, 29-dibenzoyl karounitriol in Gualou-Xiebai.
