Asymmetry of Auditory Event-Related Potential P300 in Patients with Schizophrenia.
- Author:
Yang Whan JEON
1
;
Sang Ick HAN
Author Information
1. Department of Neuropsychiatry, Our Lady of Mercy Hospital, The Catholic University of Korea, Inchon.
- Publication Type:Original Article
- Keywords:
Schizophrenia;
P300;
Asymmetry
- MeSH:
Automatic Data Processing;
Diagnostic and Statistical Manual of Mental Disorders;
Electrodes;
Event-Related Potentials, P300;
Evoked Potentials*;
Humans;
Schizophrenia*
- From:Journal of Korean Neuropsychiatric Association
2001;40(1):135-141
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The present study was designed to investigate whether asymmetry of auditory event-related potential P300 was shown in patients with schizophrenia or not. METHOD: The subjects were composed of patients(N=20) with schizophrenia by DSM-IV and normal controls(N=20). The auditory event related potential P300 was measured by "oddball paradigm". P300 component was determined by classic method at 5 electrodes(Fz, Cz, Pz, T3, T4). RESULTS: P300 amplitudes of patients were smaller than those of controls across all electrodes. Asymmetry of auditory event-related potential P300 was not shown between patients with schizophrenia and normal controls. CONCLUSION: It is implicated that auditory event-related potential P300 and its information processing should not be elicited asymmetrically in schizophrenia.
