Effects of Sulfur Fumigation on Intestinal Absorption of Chrysanthemum Flos

Author: You-Lian LI ¹
Author Information

1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Publication Type:Journal Article
Keywords: Chrysanthemum Flos; Everted intestinal sacs; Sulfur fumigation; UPLC-QTof-MS
From: Chinese Pharmaceutical Journal 2017;52(7):553-559
CountryChina
Language:Chinese
Abstract: OBJECTIVE: In previous studies, it was found that sulfur fumigation had a destructive effect on chemical constituents of Chrysanthemum Flos. To explore the intestinal absorption of Chrysanthemum Flos after sulfur fumigated. METHODS: The everted rat intestinal sacs were used, and the absorbed was analyzed constituents by UPLC-QTof-MS and HPLC. RESULTS: For sulfur fumigated Chrysanthemum Flos, the contents of flavonoid glycosides were declined in intestinal absorption, while the contents of flavonoid aglycones were not obviously increased. CONCLUSION: Sulphur fumigation lead to the changes of Chrysanthemum Flos, which affects its intestinal absorption.