Recent Progress of Particle Design Engineering Based on Surface Free Energy

Author: Liang-Shan MING ¹
Author Information

1. Engineering Research Center of Modern Preparation of TCM, Ministry of Education, Shanghai University of Traditional Chinese Medicine
Publication Type:Journal Article
Keywords: Cohesion-adhesion model spreading coefficient; Dispersive-polar model; Particle design; Surface free energy
From: Chinese Pharmaceutical Journal 2017;52(14):1201-1207
CountryChina
Language:Chinese
Abstract: Presently interests are growing in the field of surface free energy(SFE). With the further research, more particle design engineering based on SFE are summarized via characterizing the related properties of SFE during the process of particle design. SFE of materials will vary with changing the physical properties of particles via modifying the surface of particles with particle design. In this study, we summarized the application of SFE in powder micronization, particle modification, mixing, coating, pelletilization and granulation, etc. Dispersive-polar model and adhesion-cohesion model were established based on the parameters of SFE. The application of the two models were also illustrated in the particle design engineering.