Comparison of Heart Rate Variability in Kidney Transplantation and End-Stage Renal Disease Patients on Dialysis.
- Author:
Hee Ryong LEE
1
;
Joon Seok OH
;
Seung Ho CHOI
;
Peel JUNG
;
Tae Hyun RYU
;
Sung Min KIM
;
Yong Hun SIN
;
Joong Kyung KIM
;
Woo Hyung BAE
;
Taek Jong HONG
Author Information
1. Department of Internal Medicine, Bong Seng Memorial Hospital, Busan, Korea. kidney119@hotmail.com
- Publication Type:Original Article
- Keywords:
Ambulatory;
Electrocardiography;
Heart rate;
Kidney transplantation
- MeSH:
Autonomic Nervous System;
Dialysis;
Electrocardiography;
Electrocardiography, Ambulatory;
Heart;
Heart Rate;
Humans;
Kidney;
Kidney Failure, Chronic;
Kidney Transplantation;
Korea
- From:Korean Journal of Medicine
2012;83(5):606-612
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Heart rate variability (HRV) is a method for evaluation of autonomic nervous system activity by expressing the balance of sympathetic and parasympathetic tones. Some studies of HRV in patients with end-stage renal disease (ESRD) have been performed in Korea. However, few have examined kidney transplantation (KT) patients. Therefore, we investigated autonomic nervous system activity by means of HRV in patients with KT due to ESRD. METHODS: We compared the pattern of cardiac sympathetic and parasympathetic activity by time- and frequency-domain analysis of HRV with 24-h Holter monitoring of 23 KT and 56 dialysis patients. Patients underwent KT between January, 2008 and June, 2011. RESULTS: The mean ages of KT and dialysis patients were 54.2 +/- 12.3 and 53.7 +/- 12.6 years, respectively. The KT group showed increased time- and frequency-domain HRV (including HRV index), very low frequency (VLF), means and standard deviations of all normal R-R intervals for all 5-min segments of the entire recording (SDNNi), low frequency (LF), LF in normalized units (LF norm), and LF to high-frequency power ratio, compared with the dialysis group. CONCLUSIONS: Autonomic tone in patients with KT is higher than that in patients with ESRD on dialysis.
