Primary Hyperparathyroidism with Ectopic Parathyroid Adenoma Detected by Both 99mTc-MIBI SPECT and Contrast-Enhanced Neck CT.
- Author:
Hye Jin LIM
1
;
Dong Geum SHIN
;
Jun Bong KIM
;
Jin Taek KIM
;
Hyo Jeong KIM
;
Man Sil PARK
;
Ho Jeong LEE
Author Information
1. Department of Internal Medicine, Eulji University School of Medicine, Seoul, Korea. kimhj@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Hyperparathyroidism, primary;
Parathyroid neoplasms;
Technetium Tc 99m-sestamibi;
Tomography, emission-computed, single-photon
- MeSH:
Adenoma;
Dyspepsia;
Headache;
Humans;
Hypercalcemia;
Hyperparathyroidism;
Hyperparathyroidism, Primary;
Male;
Mediastinum;
Middle Aged;
Neck;
Osteoporosis;
Parathyroid Glands;
Parathyroid Neoplasms;
Technetium Tc 99m Sestamibi;
Tomography, Emission-Computed, Single-Photon;
Ureter
- From:Korean Journal of Medicine
2012;83(5):641-646
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
An ectopic parathyroid gland is a major cause of persistent and recurrent hyperparathyroidism. Surgical success depends on accurate preoperative localization of the parathyroid adenoma. We herein report the case of a 52-year-old male patient who suffered from primary hyperparathyroidism for several years. He initially presented with urinary frequency, hypercalcemia, and a ureter stone. Ultrasonography and a 99mTc-sestamibi scan were performed, but failed to localize the parathyroid lesion. Four years later, the patient revisited our hospital, complaining of general weakness, headache, dyspepsia, and recurrent urinary symptoms secondary to persistent primary hyperparathyroidism. In addition, renal function was decreased and severe osteoporosis was found. We performed a 99mTc-sestamibi scan with single photon emission computed tomography (99mTc-MIBI SPECT) and contrast-enhanced neck CT, and detected an ectopic parathyroid adenoma in the upper anterior mediastinum. In conclusion, the combination of both 99mTc-MIBI SPECT and neck CT could permit better preoperative parathyroid localization, especially for mediastinal adenomas.
