Chemical Constituents from Buddleja officinalis

Author: Guo-Yong XIE ¹
Author Information

1. Department of Resources Science of Traditional Chinese Medicines, China Pharmaceutical University
Publication Type:Journal Article
Keywords: Acacetin-7-O-glucuronide; Apigenin-7-O-glucuronide; Buddleja; Buddleja officinalis; Crocin II
From: Chinese Pharmaceutical Journal 2017;52(21):1893-1898
CountryChina
Language:Chinese
Abstract: OBJECTIVE: To study the chemical constituents from the flower buds and inflorescences of Buddleja officinalis. METHODS: Various chromatographic techniques such as silica gel and Sephadex LH-20 chromatography were used in this experiment. RESULTS: Sixteen compounds were isolated from the medicinal plant, and their structures were identified as follows acacetin(1), apigenin(2), luteolin(3), acacetin-7-O-glucoside(4), cosmosiin(5), luteolin-7-O-glucoside(6), acacetin-7-O-glucuronide(7), apigenin-7-O-glucuronide(8), linarin(9), luteolin-7-O-rutinoside(10), neobudofficide(11), acteoside(12), crocin III(13), crocin II(14), crocin I(15), and N1, N5, N10-(E)-tri-p-coumaroylspermidine(16). CONCLUSION: Compounds 4, 7, 8, 14-16 are obtained from the medicinal plant for the first time, and compounds 7, 8, 14-16 are obtained from Loganiaceae for the first time.