Status of Quality Control of Traditional Chinese Medicines Containing Calculus Bovis and Its Substitutes
- VernacularTitle: 含牛黄中成药的质量控制现状
- Author:
Xiao-Ru HU
1
Author Information
- Publication Type:Journal Article
- Keywords: Artificial Calculus Bovis; Calculus Bovis; Chinese patent drug; In vitro-cultured Calculus Bovis; Quality status
- From: Chinese Pharmaceutical Journal 2019;54(17):1374-1379
- CountryChina
- Language:Chinese
- Abstract: Calculus Bovis is the dry gall-stone of Bos taurus domesticus Gmelin, which is the most precious traditional Chinese medicine for its incomparable therapeutic effects. In vitro cultured Calculus Bovis,cultured Calculus Bovis and artificial Calculus Bovis are developed as the substitutes of Calculus Bovis. The Chinese Pharmacopoeia 2015 edition includes 89 Chinese patent drugs containing cow-bezoar and its substitutes. In this paper, the standards of Calculus Bovis and its substitutes in 89 Chinese patent drugs were reviewed to provide suggestions and reference for improving the relative standards. The qualities of Calculus Bovis and its substitutes of several Chinese patent drugs were summarized and analyzed based on the quality research of these drugs in recent years to offer suggestions for the revision of quality standards of relevant drugs and regulatory policy.
