Progress of Electrospinning Drug-loaded Fibers and Application in Transdermal Drug Delivery System
- Author:
Pei-Wen YE
1
Author Information
- Publication Type:Journal Article
- Keywords: Drug-loaded nanofiber; Electrospinning technology; Transdermal drug delivery system
- From: Chinese Pharmaceutical Journal 2019;54(24):2034-2042
- CountryChina
- Language:Chinese
- Abstract: Electrospinning technology opens up a new method for the construction of drug delivery system. The unique fiber structures of drug-loaded electrospinning nanofibers with the characteristics of similar to the extracellular matrix,good air permeability and hygroscopicity are very suitable for transdermal drug delivery systems.In this paper, the definition, characteristics, matrix selection, preparation methods, drug-loaded forms and drug-released profiles of drug-loaded electrospinning nanofibers are summarized and analyzed. Meanwhile, the application of drug-loaded electrospinning nanofbiers in the transdermal drug delivery systems is analyzed. This review is to provide support for the further studies on electrospun nanofiber transdermal drug delivery system.
