Progress in Development of Long-acting Delivery Systems for Local Anesthetics and Its Application in Postoperative Analgesia
- VernacularTitle: 局部麻醉药长效递送系统的开发及其在术后镇痛中的应用进展
- Author:
Ru-Ying CHEN
1
Author Information
- Publication Type:Journal Article
- Keywords: Local anesthetics; Long-acting; Postoperative analgesia
- From: Chinese Pharmaceutical Journal 2020;55(9):709-714
- CountryChina
- Language:Chinese
- Abstract: Patients require proper pain relief after surgery. Local anesthetics are widely used to control postoperative pain, but their clinical application is limited due to short duration of action. In decades of research, the long-acting delivery systems have been applied to local anesthetics, with the purpose of locally and continuously release drugs to prolong the action of drugs and reduce the side effects. The study of local anesthetics long-acting delivery systems has laid foundation for clinical postoperative analgesia.This paper reviewed the research status of long-acting drug delivery systems for local anesthetics, and discussed the advantages and existing problems.
