Chemical Constituents from the Aerial Parts of Korean Medicinal Herba Artemisiae sacrorum
- VernacularTitle: 朝鲜族药材万年蒿地上部分化学成分研究
- Author:
Yan-Tao SUN
1
Author Information
- Publication Type:Journal Article
- Keywords: Artemisia; Artemisia sacrorum; Chemical constituent; Lariciresinol-4'-O-β-D-glucopyranoside; Lariciresinol-4-O-β-D-glucopyranoside; Sesquiterpenoid
- From: Chinese Pharmaceutical Journal 2020;55(10):806-810
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To isolate and purify the reference compounds and improve the quality standard of Korean medicinal Herba Artemisiae sacrorum. METHODS: The chemical constituents were isolated from the aerial parts of Korean medicinal herb Artemisia sacrorum by silica gel, ODS column chromatography and preparative HPLC, and the structures were identified by NMR and MS. RESULTS: Fourteen known compounds were isolated and identified as follows:1α-acetoxyeudesm-4-en-6β,11βH-12,6-olide(1),(11S)-3-oxoeudesma-1,4(15)-dieno-12,6α-lactone(2), 1-epi-dehydroisoerivanin(3), 11-epi-taurin(4), chrysanthemolide(5), 1α-acetyl-gallicadiol(6), erivanin(7), 1α, 4α-dihydroxyeudesm-2-en-5α, 6β, 11βH-12, 6-olide(8), vulgarin(9),(+)-dehydrovomifoliol(10), isoevodionol(11),(+)-epi-pinoresinol(12), lariciresinol-4'-O-β-D-glucopyranoside(13), and lariciresinol-4-O-β-D-glucopyranoside(14). CONCLUSION: All compounds are obtained from this plant for the first time. These compounds can be used as reference substances for the quality control of this ethnic medicine.
