Research development on the immumodulatory effect of polysaccharide and its mechanism
- Author:
Hong-Liang CHEN
1
Author Information
1. Qilu Parmaceutical Factory
- Publication Type:Journal Article
- Keywords:
Gene expression;
Immunomodulation;
Polysaccharides;
Receptor;
Signal transduction
- From:
Chinese Pharmacological Bulletin
2002;18(3):249-252
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharides are important large molecules in the body. It has many functions such as activating the lymphocytes like T, B, NK and Mφ cells, promoting the secretion of cytokines and antibodies through binding to the CR3 receptor of lymphocytes, affecting the concentrations of cellar [Ca2+]i, cAMP, NO and PGE2, and promoting the gene expression of cytokines. Its function also relate to its molecule weight and structure.
