Exosomes: An endogenous natural nano-drug delivery system
10.3969/j.issn.1001-1978.2019.03.004
- Author:
Piao-Piao WANG
1
Author Information
1. Anhui University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Anti-tumor drugs;
Drug delivery system;
Drug targeting;
Exosomes;
Extortion and separation;
Tumors
- From:
Chinese Pharmacological Bulletin
2019;35(3):309-314
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are naturally nanometer-sized (40-100 nm) vesicles that contribute to the communication among the cells through the proteins, lipids and RNA which they carried. Exosomes derived at different physiological conditions play different role, which therefore can be widely used in the diagnosis and treatment of cancer. Besides, exosomes as the natural nanomaterials have the unique advantage in drug delivery system. Although the intrinsic advantages of exosomes have evoked a surge of interest, improvements in standardized isolation techniques with high efficiency and robust yield are still a huge challenge. Here, we provide an overview of the isolation and the application of exosomes in drug delivery system.
