The pharmacokinetics, toxicology and pharmacology of oxymatrine
10.3969/j.issn.1001-1978.2019.07.003
- Author:
Pei-Pei GAO
1
Author Information
1. School of Life Science and Technology, Xian Jiaotong University
- Publication Type:Journal Article
- Keywords:
Cognitive function;
Metabolism;
Oxymatrine;
Pharmacokinetics;
Pharmacology;
Toxicology
- From:
Chinese Pharmacological Bulletin
2019;35(7):898-902
- CountryChina
- Language:Chinese
-
Abstract:
Oxymatrine, the main active monomer composition of Sophora flavescens and Sopkoroa alopecuroides L. , has been used in clinic in China with many pharmacological effects, such as anti-inflammation, scavenging free radicals, inhibiting tumor cell proliferation and improving insulin resistance. It may have important clinical application prospects in aging related metabol-ic and cognitive degeneration. This article reviews the current research status of oxymatrine in pharmacokinetics, toxicology and pharmacology.
