Review of detection methods for neutrophil extracellular traps (NETs)
10.3969/j.issn.1001-1978.2019.12.005
- Author:
Yu-Ting WANG
1
Author Information
1. College of Pharmacy, Jiangxi Science and Technology Normal University
- Publication Type:Journal Article
- Keywords:
Circulating free DNA;
Flow cytometry;
Im-munochromatography;
Myeloperoxidase;
Neutrophil extracellular traps;
Neutrophilelastase
- From:
Chinese Pharmacological Bulletin
2019;35(12):1646-1649
- CountryChina
- Language:Chinese
-
Abstract:
Neutrophil extracellular trap nets (NETs) are complex networks of proteins and DNA. Many studies have shown that NETs are important participants in the pathophysiological processes of various immune inflammatory diseases, thrombosis, cancer and so on. The dynamic changes of NETs at each stage can predict the course of the disease to a certain extent. This article systematically reviews the current detection methods for ef-fectively quantifying NETs in order to provide the latest theoretical reference for the early detection of chronic inflammation and targeted therapy of cancer.