Role of gut microbiota in chronic liver disease and its potential therapeutic strategies
10.3969/j.issn.1001-1978.2020.01.005
- Author:
Hang SHI
1
Author Information
1. School of Pharmacy
- Publication Type:Journal Article
- Keywords:
Alcoholic liver disease;
Gut microbiome;
Hepatocellular cancer;
Nonalcoholic fatty liver disease;
Primary sclerosing cholangitis;
Therapeutic strategies
- From:
Chinese Pharmacological Bulletin
2020;36(1):18-21
- CountryChina
- Language:Chinese
-
Abstract:
An increasing number of studies have shown that intestinal microbes play an important role in maintaining liver homeostasis. The liver is closely linked to the intestine through the portal vein, and the transfer of intestinal microbcs, and their metabolites to the liver can affect the normal physiological function of the liver. Willi the deepening of research on intestinal microbes in recent years, a large number of studies have found that intestinal microbes play an important role in the development of chronic liver diseases. and more and more studies have shown that the regulation of intestinal microbes may be a potential therapeutic target for chronic liver diseases. This article summarizes the role of intestinal microbes in the development of chronic liver diseases and its related mechanisms in recent years, aiming to provide a reference for the prevention and treat-ment of chronic liver diseases.
