Current study of trib3 and diseases
10.3969/j.issn.1001-1978.2020.01.003
- Author:
Ling LI
1
Author Information
1. Fifth Affiliated Hospital of Sun Yal-sen University, Dept of Pharmacy
- Publication Type:Journal Article
- Keywords:
Cancer;
Cardiovascular diseases;
Diabetes;
Nervous system diseases;
Pharmacogenomics;
Trib3
- From:
Chinese Pharmacological Bulletin
2020;36(1):9-12
- CountryChina
- Language:Chinese
-
Abstract:
TRIB3 is a pseudokinase that binds to a variety of proteins in eukaryotic cells and mediates the development of diabetes, cancer, cardiovascular diseases and nervous system diseases, but their mutual regulatory relationship and molecular mechanisms have not yet been elucidated. This article reviews the diseases and regulatory pathways involved in TRIB3, in or-der to provide clues and evidence for finding common molecular mechanisms of the pathogenesis of diabetes, cancer and cardiovascular diseases.
