REGUL ATORY EFFECT OF SIMVASTATIN ON MIDDLE/L ATE STAGES OSTEOGENIC DIFFERENTIATION OF BONE MARROW MESENCHYMAL STEM CELLS VIA p38MAPK PATHWAY
10.7507/1002-1892.20160208
- Author:
Kezhong ZHANG
1
Author Information
1. North China University of Science and Technology
- Publication Type:Journal Article
- Keywords:
Bone marrow mesenchymal stem cells;
Osteocalcin;
Osteogenic differentiation;
Phospho-p38;
Simvastatin
- From:
Chinese Journal of Reparative and Reconstructive Surgery
2016;30(8):1038-1043
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate the regulatory effect of simvastatin on osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) at middle/late stages by p38MAPK pathway under condition of osteoinductive environment.
