A Case of Acute Renal Failure Caused by Cresol Ingestion.
- Author:
Hye Suk HAN
1
;
Hag Ei KIM
;
Young Ook EUM
;
Su In YOON
;
Joungho HAN
;
Ki Won MOON
;
Soon Kil KWON
;
Hye Young KIM
;
Kyung Sook LEE
Author Information
1. Department of Internal Medicine, College of Medicine, Chungbuk National University, Korea. kwon@chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Cresol;
Intoxication;
Acute renal failure
- MeSH:
Acute Kidney Injury*;
Adsorption;
Adult;
Burns, Chemical;
Eating*;
Humans;
Inhalation;
Korea;
Male;
Suicide, Attempted
- From:Korean Journal of Nephrology
2005;24(2):342-345
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cresol, a commonly used disinfectant, is an extremly toxic material and can cause systemic effects such as respiratory, neurological, gastrointestinal, hepatic and renal damage. Cresol intoxication can be caused by inhalation, cutaneous adsorption or oral ingestion. Cresol denatures and precipitates cellular proteins, thus exer ts their toxic effects directly on all cells. There is only one case of cresol intoxication in Korea, but a case of chemical burn. We report a case of acute renal failure caused by cresol ingestion. A 39-year-old male attempted suicide by ingesting 200 mL of 50% cresol solution. Acute renal failure developed, but he recovered by only supportive care. It was reported that the lethal dose of saponated cresol solution is approximately 60-120 mL and the lethal blood level is 71-190 microgram/mL. The amount of cresol ingested by the patient far exceeded the reported lethal dose. This is the first case of acute renal failure caused by cresol ingestion successfully treated with only supportive care in Korea.
