Reversible splenial lesion on the corpus callosum in nonfulminant hepatitis A presenting as encephalopathy.
10.3350/cmh.2014.20.4.398
- Author:
Soon Young KO
1
;
Byung Kook KIM
;
Dong Wook KIM
;
Jeong Han KIM
;
Won Hyeok CHOE
;
Hee Yeon SEO
;
So Young KWON
Author Information
1. Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. sykwonmd@hotmail.com
- Publication Type:Case Reports
- Keywords:
Acute hepatitis A;
Encephalopathy;
Magnetic resonance imaging;
Corpus callosum
- MeSH:
Adult;
Alanine Transaminase/blood;
Corpus Callosum/*radiography;
Creatinine/blood;
Electroencephalography;
Encephalitis/complications/*diagnosis;
Hepatitis A/complications/*diagnosis;
Humans;
Magnetic Resonance Imaging;
Male;
Renal Dialysis
- From:Clinical and Molecular Hepatology
2014;20(4):398-401
- CountryRepublic of Korea
- Language:English
-
Abstract:
Reversible focal lesions on the splenium of the corpus callosum (SCC) have been reported in patients with mild encephalitis/encephalopathy caused by various infectious agents, such as influenza, mumps, adenovirus, Varicella zoster, Escherichia coli, Legionella pneumophila, and Staphylococcus aureus. We report a case of a reversible SCC lesion causing reversible encephalopathy in nonfulminant hepatitis A. A 30-year-old healthy male with dysarthria and fever was admitted to our hospital. After admission his mental status became confused, and so we performed electroencephalography (EEG) and magnetic resonance imaging (MRI) of the brain, which revealed an intensified signal on diffusion-weighted imaging (DWI) at the SCC. His mental status improved 5 days after admission, and the SCC lesion had completely disappeared 15 days after admission.