Composite liver tumors: A radiologic-pathologic correlation.
10.3350/cmh.2014.20.4.406
- Author:
Megha NAYYAR
1
;
David K IMAGAWA
;
Temel TIRKES
;
Aram N DEMIRJIAN
;
Roozbeh HOUSHYAR
;
Kumar SANDRASEGARAN
;
Chaitali S NANGIA
;
Tara SEERY
;
P BHARGAVA
;
Joon II CHOI
;
Chandana LALL
Author Information
1. Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
- Publication Type:Case Report
- Keywords:
Hepatoceullular carcinoma;
Cholangiocarcinoma;
Bi-phenotypic tumors;
Computed tomography, Magnetic resonance imaging
- MeSH:
CA-19-9 Antigen/metabolism;
Carcinoma, Hepatocellular/mortality/pathology/radiography;
Cholangiocarcinoma/mortality/pathology/radiography;
Humans;
Liver Neoplasms/mortality/pathology/*radiography;
Magnetic Resonance Imaging;
Phenotype;
Risk Factors;
Survival Analysis;
Tomography, X-Ray Computed;
alpha-Fetoproteins/analysis
- From:Clinical and Molecular Hepatology
2014;20(4):406-410
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.
