The application of urine derived stem cells in regeneration of musculoskeletal system
10.7507/1002-1892.201804024
- Author:
Fei XING
1
Author Information
1. Department of Orthopedics, West China Hospital, Sichuan University
- Publication Type:Journal Article
- Keywords:
bone repair;
induced pluripotent stem cells;
multi-differentiation;
tissue engineering;
Urine derived stem cells
- From:
Chinese Journal of Reparative and Reconstructive Surgery
2018;32(11):1477-1482
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To review the application of urine derived stem cells (USCs) in regeneration of musculoskeletal system. Methods: The original literature about USCs in the regeneration of musculoskeletal system was extensively reviewed and analyzed. Results: The source of USCs is noninvasive and extensive. USCs express MSCs surface markers with stable proliferative and multi-directional differentiation capabilities, and are widely used in bone, skin, nerve, and other skeletal and muscle system regeneration fields and show a certain repair capacity. Conclusion: USCs from non-invasive sources have a wide application prospect in the regeneration of musculoskeletal system, but the definite biological mechanism of its repair needs further study.
