Preliminary report of trial of endarterectomy versus stenting for the treatment of carotid atherosclerotic stenosis in China (TESCAS-C)
- Author:
Feng LING
1
Author Information
1. Department of Neurosurgery
- Publication Type:Journal Article
- From:
Chinese Journal of Cerebrovascular Diseases
2006;3(1):4-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare carotid endarterectomy to carotid artery stenting for the treatment of severe symptomatic or asymptomatic atherosclerotic carotid artery stenosis. Methods: We conducted a multicenter randomized controlled trial for comparing carotid-artery stenting to endarterectomy in 166 patients with severe symptomatic or asymptomatic atherosclerotic carotid artery stenosis. The primary end point of the study was the cumulative incidence of death, stroke, or myocardial infarction within 30 days after the surgical intervention, or death or ipsilateral stroke between 31 days and 6 months. The secondary end point was the related complications of either intervention, or severe restenosis at 6 months after operation. Results: The primary end point occurred in 8 patients randomly assigned to undergo carotid artery stenting (cumulative incidence, 9.8 percent) and in 10 patients randomly assigned to undergo endarterectomy (cumulative incidence, 11.9 percent). The secondary end point occurred in 18 patients randomly assigned to undergo carotid artery stenting (cumulative incidence, 22.0 percent) and in 16 patients randomly assigned to undergo endarterectomy (cumulative incidence, 19.1 percent). Conclusion: Among patients with severe carotid-artery stenosis and coexisting conditions, the therapeutic result of carotid stenting is not inferior to that of carotid endarterectomy.
