Onyx embolization for the treatment of peripheral intracranial aneurysms: An efficacy analysis
10.3969/j.issn.1672-5921.2010.09.009
- Author:
Qi WU
1
Author Information
1. Department of Neurosurgery
- Publication Type:Journal Article
- Keywords:
Chemoembolization;
Intracranial aneurysms;
Onyx;
Therapeutic
- From:
Chinese Journal of Cerebrovascular Diseases
2010;7(9):487-490
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the clinical effect of liquid embolic agent Onyx in the treatment of peripheral intracranial aneurysms. Methods: Nine patients with 10 peripheral intracranial aneurysms were studied prospectively. Five aneurysms were in the distal posterior inferior cerebellar artery, two in the distal superior cerebellar artery, one in the distal posterior cerebral artery, and two in the distal middle cerebral artery. All patients were treated with Onyx to occlude their proximal parent arteries and aneurysms. They were followed up for 6 to 31 months. Results: The aneurysms were occluded completely in all the patients. Seven patients had a good recovery, and the Glasgow outcome scale (GOS) score was 5. One patient had left extremity paralysis before the procedure and it did not have any change alter the procedure (GOS 3); one patient died. Head CT scan was performed before discharge, only one patient showed left parietal lobe infarction, but he did not have obvious symptoms. Four patients were reexamined by DSA at 6 months after the procedure, and the aneurysms did not recurred. Four patients were followed-up clinically. No new neurological dysfunction and rebleeding were observed in all the patients. Conclusion: Onyx occlusion of aneurysms and its proximal parent arteries for treatment of peripheral intracranial artery aneurysms is safe and effective. Further clinical and imaging follow-up are needed for long-term result.
