Analysis of the distributive characteristics of cerebral arterial stenosis and its risk factors
10.3969/j.issn.1672-5921.2010.09.005
- Author:
Xiao-Hui ZHANG
1
Author Information
1. Department of Neurology (II)
- Publication Type:Journal Article
- Keywords:
Atherosclerosis;
Brain ischemia;
Lesion distribution;
Risk factors
- From:
Chinese Journal of Cerebrovascular Diseases
2010;7(9):467-472
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the distribution of cerebral artery stenosis in patients with ischemic cerebrovascular disease and its relationship with the risk factors for atherosclerosis. Methods: Three hundred seventy-seven patients with ischemic cerebrovascular disease detected by cerebral angiography were analyzed retrospectively. The location and degree of arterial stenosis were recorded by two neurologists respectively. The patients were divided into intracranial arterial lesion, extracranial arterial lesion, severe stenosis, occlusion and multiple vascular lesion groups according to the location and severity of the lesions. The risk factors for atherosclerosis were also analyzed. Results: Circled digit oneOf the 377 patients, 285 had vascular lesions. A total of 892 lesions were detected. Of those, intracranial arterial lesions were 438 (49.1%) , intracranial arterial lesions were 454 (50.9%). The former was most commonly observed in the extracranial internal carotid arteries (19. 6% , 175/892) , and the latter was mostly seen in the extracranial internal carotid arteries (15.0%, 134/892) and middle cerebral arteries (12.4%, 111/892). Circled digit twoAmong the extracranial arteries, the stenotic degree of vertebral artery and extracranial internal carotid artery were most severe. There were statistical significance as compared to the common carotid artery (P < 0.05); while in the intracranial arteries the stenotic degree of anterior cerebral artery and middle cerebral artery were most severe. Circled digit threeThe proportion of patients with intracranial arterial lesion alone complicating hypertension was higher than those with extracranial arterial lesion alone(80.39% vs. 59.42%). There were significant difference ( P = 0.015). The multiple risk factors for atherosclerosis in patiente with server vascular lesion were higher than those in the angiographically normal patients. Conclusions: The intracranial arterial lesion in patients with ischemic cerebrovascular disease was slightly more than that of extracranial artery. The stenotic degree in vertebral artery, extracranial internal carotid artery, anterior cerebral artery, and middle cerebral artery are more severe. The proportion of the patients with intracranial arterial lesion alone and complicating hypertension is significantly higher than that of the patients with extracranial arterial lesion alone. With the increase of the risk factors for arteriosclerosis, the probability of severe vascular stenosis will increase on cerebral angiography.
