Correlation between ankle-brachial index and carotid atherosclerotic stenosis in geriatric patients with ischemic stroke
10.3969/j.issn.1672-5921.2010.10.007
- Author:
He-Jin LIU
1
Author Information
1. Department of Cadre Health Care
- Publication Type:Journal Article
- Keywords:
Aged;
Ankle-brachial index;
Atherosclerosis;
Brain ischemia;
Carotid stenosis;
Stroke
- From:
Chinese Journal of Cerebrovascular Diseases
2010;7(10):533-536
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the correlation between the ankle-brachial index (ABI) and carotid atherosclerotic stenosis (CAS) in geriatric patients with ischemic stroke. Methods: A total of 190 geriatric patients with ischemic stroke were selected. Their relevant risk factors and laboratory data were collected. The ABI measurements and carotid ultrasonography were performed. The patients were divided into either a non-stenosis group (stenosis <50%) or a stenosis group (stenosis ≥50%) according to the examination by color Doppler ultrasonography. Results: Circled digit oneThe prevalence of abnormal ABI in the stenosis group and non-stenosis group were 59.1% (26/44) and 29.5% (43/146) respectively. The ABI value (0.81 ±0.23) in the stenosis group was lower than 0.99 ±0.18 in the non-stenosis group. The difference was statistically significant (P < 0.001). The age and prevalence of diabetes in the stenosis group were significantly higher than those in the non-stenosis group (P = 0.005, P < 0.001). Circled digit twoThe multivariate Logistic regression analysis showed that diabetes (OR = 4.206, 95% CI: 1.957-9.040) and abnormal ABI (OR = 3.385, 95% CI: 1.630-7.031) were the independent correlation factors for CAS of ≥50% (P < 0.001). Circled digit threeThe correlation analysis showed that ABI was negatively correlated with carotid intima-media thickness (IMT) (r = -0.320) and the severity of CAS (r, = -0.365) (P < 0.001). Conclusion: The decreased ABI in geriatric patients with ischemic stroke is independently correlated to CAS of ≥50% , and the ABI value is negatively correlated with IMT and the severity of CAS.