Effects of anterior communicating artery patency on the hemodynamic alteration of contralateral extracranial-intracranial artery after severe unilateral internal carotid artery stenosis or occlusion
10.3969/j.issn.1672-5921.2011.11.002
- Author:
Ling-Yun JIA
1
Author Information
1. Department of Vascular Ultrasonography
- Publication Type:Journal Article
- Keywords:
Anterior communicating artery;
Collateral circulation;
Hemodynamics;
Internal carotid artery diseases;
Ultrasonography, Doppler
- From:
Chinese Journal of Cerebrovascular Diseases
2011;8(11):565-569
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of anterior communicating artery (ACoA) patency on the hemodynamic alteration in contralateral extracranial-intracranial artery after severe stenosis (70% to 99%) or occlusion of unilateral extracranial internal carotid artery (ICA). Methods: Two hundred twenty-eight patients with severe unilateral ICA stenosis or occlusion and normal or stenosis <50% (referred to relatively normal) of the contralateral ICA were enrolled in the study. Among them, there were 113 patients with and 115 without patent ACoA. Color Doppler flow imaging (CDFI) was used to measure the diameters of bilateral proximal ICA, the peak systolic velocity (PSV), the end-diastolic flow velocity (EDV), and the vascular resistance index (RI). Transcranial Doppler (TCD) was used to measure the PSV, EDV, and pulsatility index (PI) of the bilateral middle cerebral artery (MCA) and anterior cerebral artery (ACA). The effects of ACoA patency on the hemodynamics of ICA, MCA and ACA of the relatively normal side were analyzed. Results: Circled digit oneThere was no significant difference in the diameter of ICA on the relatively normal side between the ACoA unpatent group and the ACoA patent group. The PSV and EDV on the relatively normal side in the ACoA patent group were higher than those in the ACoA unpatent group (P < 0.000) while the RI was lower than that in the ACoA unpatent group (P = 0.001). Circled digit twoThe PSV and EDV of MCA and ACA on the ICA relatively normal side in the ACoA patent group were higher than those in the ACoA unpatent group (P = 0.000) and the PI was lower than that in the ACoA unpatent group, however, there was significant difference only in PI of ACA between the two groups (P = 0.007). Circled digit oneThe correlation analysis showed that the mean velocity of MCA and ACA on the relatively normal side was positively correlated with that of ICA (r = 0.587, 0.346, P = 0.000). Conclusion: When one side of ICA is severely stenotic or occlusion, the ACoA patency will directly influence the hemodynamic alteration of the extracranial ICA as well as MCA and ACA on the other side.
