Advances of "help-me" signals from neurons after focal brain injuries
10.3969/j.issn.1672-5921.2019.09.010
- Author:
Yunxia DUAN
1
Author Information
1. China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University
- Publication Type:Journal Article
- Keywords:
Brain injury;
Cell signal;
Neuron;
Neuroprotection;
Review;
Stroke
- From:
Chinese Journal of Cerebrovascular Diseases
2019;16(9):495-499
- CountryChina
- Language:Chinese
-
Abstract:
Injured neurons will send "help-me" signals to nearby cells after focal injuries. These neurons will be protected by proliferation of neural progenitors, transformation of microglia, and proliferation of endothelial cells. This article provides an in-depth review of the latest research on endogenous " helpme" signals after neuronal injury, especially after cerebral ischemia injury was made, suggesting findings of endogenous "help-me" signals after neuronal injury and its usage as a novel target for intervention may provide new ideas and methods for neuroprotection researches.