Health-related quality of life in patients with asymptomatic unruptured intracranial aneurysms after endovascular treatment
10.3969/j.issn.1672-5921.2019.12.002
- Author:
Xiaodong ZHAI
1
Author Information
1. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University
- Publication Type:Journal Article
- Keywords:
Ability to work;
Endovascular treatment;
Health-related quality of life;
Intracranial aneurysm;
Unruptured intracranial aneurysm
- From:
Chinese Journal of Cerebrovascular Diseases
2019;16(12):621-627
- CountryChina
- Language:Chinese
-
Abstract:
Objective: The aim of this study was to analyze the health-related quality of life (HRQoL) and their influencing factors in patients with asymptomatic unruptured intracranial aneurysms (UIAs) after endovascular treatment. Methods: We retrospectively reviewed 44 patients with asymptomatic UIAs (56aneurysms) received endovascular treatment in Xuanwu Hospital of Capital Medical University from January 2015 to May 2017. The average follow-up time was (28 ±9) month. The clinical data of patients were collected, and the HRQoL was evaluated by the SF-36 questionnaire. The SF-36 results and influencing factors were analyzed. Results: Forty-four patients with UIAs in this study showed significantly lower body pain,physical function,and mental health in the three dimensions of the SF-36 scale than the normal population in China (75 ± 15,82 ± 15 and 71 ± 14 vs. 83 ±20,88 ± 17 and 79 ± 15;t =2.89,2. 14 and 3. 34 Respectively; all P < 0. 05). The results of univariate analysis showed (hat the Mental Component Summary score (MCS) of patients with sleep duration < 6 h and ≥6h were respective 63 ± 18 and 79 ± 14points (t = -2.41);the MCS score of patients with disease duration ≤3 months and > 3 months were respective 76 ±15 and 89 ± 7 points (t = -2. 11); the differences were significant (both P < 0. 05). The physical component summary score (PCS) of sleep duration < 6 h and ≥ 6 h were respective 63 ± 22 and 77 ± 17 (t = - 2. 11); the PCS of ≤3 months and > 3 months were respective 73 ± 17 and 90 ± 5 (l = -2.74);the differences were significant (both P <0.05). Multivariate analysis showed that the course of disease ≤ 3 months was the independent risk factor of PCS (95% CI 2. 23 -27. 42, P = 0. 02), and sleep time<6h was the independent risk factor of MCS (95% CI 1. 44 -28. 92, P = 0. 03). 12.5% (4/32) of these patients failed to recover to normal work before treatment even after long-term recovery (28 ± 9 months). Conclusions: HRQoL results in patients with asymptomatic UIAs after endovascular treatment were lower than those in the general population in multiple dimensions of SF-36. The course of disease ≤3 months and daily sleep time < 6h are independent risk factors for PCS and MCS,respectively.
