Progress in the treatment of multiple myeloma
10.12092/j.issn.1009-2501.2020.01.016
- VernacularTitle: 多发性骨髓瘤的治疗进展
- Author:
Xiangxiang CHANG
1
Author Information
1. Graduate School of Wannan Medical College
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell transplantation;
Immunomodulator;
Immunotherapy;
Multiple myeloma;
Proteasome inhibitor
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2020;25(1):107-116
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma is a malignant tumor that occurs in plasma cells. Clonal plasma cells in bone marrow proliferate abnormally and secrete monoclonal immunoglobulin or its fragment (M protein), resulting in damage to related organs or tissues. At present, with the development of new drugs, the development of cellular immunotherapy and the improvement of hematopoietic stem cell transplantation technology, the depth of remission and survival of multiple myeloma are significantly prolonged. This article reviews the latest advances in the treatment of multiple myeloma in recent years.