Development of therapeutic biologics in cancer treatment
10.12092/j.issn.1009-2501.2020.01.005
- VernacularTitle: 生物药在肿瘤治疗领域的临床研究进展
- Author:
Kaiting ZHANG
1
Author Information
1. Pfizer (China) Research and Development Co., Ltd
- Publication Type:Journal Article
- Keywords:
Cancer treatment;
Immunotherapy;
Targeted therapy;
Therapeutic biologics
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2020;25(1):32-43
- CountryChina
- Language:Chinese
-
Abstract:
Cancer treatment is always the focus of pharmaceutical development while therapeutic biologics play an important role alongside. This review is focused on the development of therapeutic biologics in cancer treatment and categorized by targeted therapy and immunotherapy by mechanism. In targeted therapy, monoclonal antibodies, biosimilars and antibody-drug conjugates are discussed in details, while for immunotherapy, checkpoint inhibitors, T-cell transfer therapy and bispecific antibody are introduced, respectively.
