Advances in research on long non-coding RNA in drug resistance of colorectal cancer
10.12092/j.issn.1009-2501.2020.07.012
- VernacularTitle: 长链非编码RNA在结直肠癌耐药中的研究进展
- Author:
Ziyuan WANG
1
Author Information
1. Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
Drug resistance;
Long non-coding RNA
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2020;25(7):796-802
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is the third most prevalent cancer in the world. Surgical resection is the preferred method for the treatment of colorectal cancer, assisted by chemotherapy, targeted therapy and other methods to reduce recurrence and metastasis. However, drug resistance is an important factor in postoperative recurrence and death. Long non-coding RNA (lncRNA) has been found to be involved in drug resistance of colorectal cancer. Therefore, it is of great significance to study the mechanism of lncRNA regulating drug resistance in colorectal cancer. This paper reviewed the progress of lncRNA in drug resistance of colorectal cancer.