Materiomic release kinetics of Longdan Xiegan Pill
- Author:
Zhen GUO
1
Author Information
1. College of Pharmaceutical Sciences
- Publication Type:Journal Article
- Keywords:
Longdan Xiegan Pill;
Materiome of Chinese materia medica;
Release dynamics;
UV-vis
- From:
Chinese Traditional and Herbal Drugs
2010;41(11):1806-1808
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study materiomic release kinetics of Longdan Xiegan Pill. Methods: The materiomics release kinetics, the release profiles, and the multidimensional release characteristic of Longdan Xiegan Pill were determined by the paddle method with a rotate speed at 100 r/min in Chinese Pharmacopia, and the materiome was quantified by UV-vis combined Kalman filter method. Results: Longdan Xiegan Pill behaved typical sustained release profile which was consistent with Weibull and Higuchi release models. Conclusion: The sustained release profile of Longdan Xiegan Pill is depicted quantitatively by materiomic release dynamics in this paper, which demonstrates the obvious sustained release characteristic of the traditional pills.
