Best pre-treatment method and its technology before ultrafiltration refination of Reduning water extract
- Author:
Wen-Ling FAN
1
Author Information
1. College of Pharmacy
- Publication Type:Journal Article
- Keywords:
Pre-treatment;
Reduning water extract;
Ultrafiltration membrane refination
- From:
Chinese Traditional and Herbal Drugs
2010;41(11):1793-1796
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the best pre-treatment method and its technology before ultrafiltration of Reduning water extract. Methods: To investigate such pre-treatment methods as chitosan flocculation on the impurity of prescription water extract, as well as polysulfone ultrafiltration membrane refination effect with molecular weight cut-off three to five million. Results: The centrifugation and decompress filtration were not benefit to promote the geniposide reservation and reduce fouling degree of membrane. Absorption of active carbon could make the geniposide reservation deeply lower. The geniposide was reserved mostly and the total extracts reduced mostly for chitosan flocculation and microfiltration. But the flux was higher and the membrane fouling is smaller after chitosan flocculation. Conclusion: Chitosan flocculation is the best pre-treatment method. The operating conditions are that temperature of Reduning water extract is 70°C, pH value 6, and the dosage of 1% chitosan is 70 mL/L.