Chemical constituents in roots of Ilex cornuta
- Author:
Lin-Lin FAN
1
Author Information
1. School of Pharmacy
- Publication Type:Journal Article
- Keywords:
3β-acetoxy-28-hydroxyurs-12-ene;
Betulonic acid;
Hede-ragenin;
Ilex cornuta Lindley;
Triterpenoid
- From:
Chinese Traditional and Herbal Drugs
2011;42(2):234-236
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of the roots of Ilex cornuta. Methods: The compounds were isolated and purified by silica gel, Sephadex LH-20, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectroscop analyses. Results: Eight compounds were isolated and their structures were identified to be β-sitosterol (1), lupeol (2), betulonic acid (3), hede-ragenin (4), 3β-acetoxy-28-hydroxyurs-12-ene (5), ursolic acid (6), 19α-hydroxy ursolic acid (7), 3β-acetoxy-ursolic acid (8), 23-hydroxyl-methyl ursolate (9), heptanoic acid (10), β-daucosterol (11). Conclusion: Compounds 4,5,8, and 9 are obtained from this genus for the first time, and compound 3 is obtained from this plant for the first time.
