Flocculation procedure of water extract from Yangyin Qingfei Syrup with ZTC 1 + 1
- Author:
Jiao SUN
1
Author Information
1. School of Chemical Engineering and Technology
- Publication Type:Journal Article
- Keywords:
Flocculation;
Retention rate;
Turbidity degree;
Water extract solution;
Yangyin Qingfei Syrup (YQS);
ZTC 1 + 1
- From:
Chinese Traditional and Herbal Drugs
2011;42(3):478-483
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the production procedure of Yangyin Qingfei Syrup (YQS), improve the clarity, and reserve more active components in water extract solution of YQS. Methods: The natural macromolecule flocculant ZTC 1 + 1 was applied to purify the solution of YQS. By analyzing the turbidity degree of the upper solution and the retention rate of glycyrrhizic acid, the influences of the dosage of flocculant, temperature, mixing speed, and time on flocculation effect were investigated and the optimum process conditions were obtained. Results: The optimum process conditions were as follows: the flocculation temperature was 30 °C, the dosage of ZTC 1 + 1 was 0.6 g/L, the fast mixing speed was 450 r/min, and the fast mixing time was 2 min, the slow mixing speed was 50 r/min and the slow mixing time was 10 min, then the treated solution was centrifuged for 20 min at 3 000 r/min. Under above conditions, the retention rate of glycyrrhizic acid was 84% and the turbidity degree was 1.3 NTU. Conclusion: Compared with ethanol precipitation, the flocculation effect of the solution of YQS with ZTC 1 + 1 has distinct advantages. Flocculation technology can replace traditional ethanol precipitation technique for purification of the solution of YQS.
