Two novel polyketides from Peperomia dindygulensis
- Author:
Wen-Jun ZHU
1
Author Information
1. Department of Traditional Chinese Materia Medica
- Publication Type:Journal Article
- Keywords:
Peperomadinone A;
Peperomadinone B;
Peperomia dindygulensis Miq;
Polyketides;
Semi-preparative HPLC
- From:
Chinese Traditional and Herbal Drugs
2011;42(3):420-423
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from Peperomia dindygulensis. Methods: The chemical constituents in chloroform fraction of ethanol extract from P. dindygulensis were isolated and purified by column chromatography over silica gel column, preparative TLC, and semi-preparative HPLC. Their chemical structures were elucidated on the basis of physicochemical and spectral data. Results: Two new polyketides were isolated from the chloroform extracting fraction of P. dindygulensis and identified as (4S)-1,4-dihydroxy-2-(1′, 13′-diketone-octadec-14′E-ene)-1-cyclohexen-3-one (1) and (4S)-1,4-dihydroxy-2-(1′,14′-diketone-octadec-12′E-ene) -1-cyclohexen-3-one (2). Conclusion: Compounds 1 and 2 are new compounds and named as peperomadinone A and peperomadinone B.
