Separation and purification of cynarin from Cynara scolymus leaves by macroporous adsorption resin
- Author:
Jian-Guang FENG
1
Author Information
1. Department of Research and Development
- Publication Type:Journal Article
- Keywords:
Cynara scolymus L;
Cynarin;
Dynamic adsorption;
Macroporous adsorption resin;
Static adsorption
- From:
Chinese Traditional and Herbal Drugs
2011;42(6):1109-1113
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the technological parameters of separation and purification of cynarin from Cynara scolymus leaves. Methods: Seven different types of macroporous adsorption resins were evaluated on absorptive capacity, desorption rate, and adsorption rate in order to select the best resin and the conditions of the best resin to separate and purify cynarin were researched. Results: It was found that LSA-21 resin showed better comprehensive adsorption property, flow rate of sample loading was 2 BV/h, 3 BV/h 50% alcohol aqueous and 2 BV/h velocity was used to elute. In this process to obtain the product with purity of 5.63% cynarin, ash content of 0.61%, product yield 5.56%, the product quality could meet the market demand. Conclusion: The LSA-21 macroporous adsorption resin shows better comprehensive adsorption property. It could be used to isolate and purify the cynarin.
