Chemical constituents of Patrinia scabiosaefolia
- Author:
Liang GAO
1
Author Information
1. College of Pharmacy
- Publication Type:Journal Article
- Keywords:
3-hydroxy-olean-11-oxo-12-en-28-oic acid;
Guaia-6-en-4, 10-diol;
Patrinia Juss.;
Patrinia scabiosaefolia Fisch.;
Triterpenoids
- From:
Chinese Traditional and Herbal Drugs
2011;42(8):1477-1480
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Patrinia scabiosaefolia. Methods: The constituents were extracted by methanol and isolated by silica gel chromatography, Sephadex LH-20 gel column chromatography, medium pressure column chromatography, and semi-preparative high performance liquid chromatography. Their structures were elucidated by chemical properties and spectroscopic analysis. Results: Fourteen compounds were isolated and their structures were identified to be 3-hydroxy-olean-11-oxo-12-en-28-oic acid (1), 3, 11-dioxoolean-12-en-28-oic acid (2), 3-O-β-D-xylopyranosyl oleanolic acid 28-O-β-D-glucopyranosyl ester (3), 29-hydroxy-3-oxo-olean-12-en-28-oic acid (4), 3β, 12α-dihydroxy-oleanan-13β, 28-olide (5), 3-O-rhamnopanosyl-(1→2)-xylopyanosyl-oleanolic acid-28-O-glucopyanosyl ester (6), guaia-6-en-4, 10-diol (7), 3-epi-ursoloic acid (8), stigmasterol (9), ergost-6, 22-dien-3β, 5α, 8α-triol (10), oleanolic acid 3-O-β-D-xylopyranoside (11), oleanolic acid 3-α-L-rhamnopyanosyl- (1→2)-β-D-xylopyranoside (12), 3-O-β-D-xylopyanosyl-(1→3)- α-L-rahmnopyanosyl-(1→2)-α-L-arabinopyanosyl oleanolic acid 28-O-β-D-glucopyranosyl ester (13), and oleanolic acid 28-O-β-D- glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (14). Conclusion: Compounds 1-8 are obtained from the plants of Patrinia Juss. for the first time.
